AI vs Jobs split scene showing robotic content writer and real construction worker

AI vs Jobs: Microsoft Reveals the 40 Most Affected and 40 Still Safe in 2025

What the Microsoft AI Study Actually Measured

This research, backed by Microsoft and published on arXiv, analyzes 200,000 real conversations between U.S. users and Microsoft Copilot (Bing AI). It studies what users ask Copilot to help with (user goals) vs what Copilot actually performs (AI actions).

They used work activity classifications from O*NET (U.S. labor data) to map AI capability across the job market. Each job received an AI Applicability Score, based on:

  • Coverage: How often AI helps with tasks from that job
  • Completion: How successfully AI completes the task
  • Scope: How broadly AI covers the job’s responsibilities

This isn’t just theory. This is based on real-world use.

40 Jobs Most Affected by AI (Top Applicability Scores)

These jobs rely on communication, research, writing, or structured processes. AI tools like Copilot, ChatGPT, and Claude are already performing many tasks in these roles.

Top 10 Most Exposed Jobs

RankJob TitleWhy AI Can Replace It Easily
1Interpreters & TranslatorsLanguage tasks, summarization, translation
2HistoriansResearch + writing + summarization
3Passenger AttendantsScripted info, safety briefings
4Sales Reps (Services)Informational, repetitive queries
5Writers and AuthorsText generation, editing, summaries
6Customer Service RepsAutomated replies, chatbots
7CNC Tool ProgrammersStructured logic + coding
8Telephone OperatorsVoice-based AI handling similar functions
9Ticket Agents and Travel ClerksAI handling bookings, schedules
10Broadcast Announcers & DJsText-to-speech, audio content creation

Others include: Editors, Journalists, Proofreaders, Technical Writers, Public Relations Specialists, Data Scientists.

40 Jobs AI Can’t Replace (Yet)

These jobs involve physical activity, on-site work, manual labor, or personal interaction. AI has little ability to directly perform these tasks.

Top 10 Least Affected Jobs

RankJob TitleWhy AI Can’t Replace It Yet
1Dredge OperatorsHands-on mechanical equipment operation
2Bridge & Lock TendersPhysical, location-specific control systems
3Water Treatment Plant OperatorsOn-site monitoring, machinery handling
4Rail Track Maintenance WorkersManual tools + safety work
5Pile Driver OperatorsEquipment control + judgment
6Floor Sanders and FinishersSkilled manual surface work
7OrderliesPhysical assistance and movement support
8Logging Equipment OperatorsOutdoor, machinery-heavy tasks
9RoofersDangerous, hands-on outdoor work
10DishwashersPhysical, repetitive kitchen work

Others include: Nurses, Phlebotomists, Firefighting Supervisors, Construction Workers, Housekeepers, and Truck Drivers.

What Makes a Job “AI Safe” or “AI Vulnerable”

Jobs Most at Risk:

  • Rely heavily on text, language, or software
  • Include repeatable tasks or structured workflows
  • Can be done remotely or digitally

Jobs Least Affected:

  • Require manual or physical presence
  • Involve unpredictable real-world settings
  • Need human touch, emotional support, or direct service

Who Should Be Paying Attention?

Anyone in the following sectors:

  • Sales & Admin Support
  • Writing, Editing, Content Creation
  • Teaching, Coaching, Training
  • Data Analysis & Market Research

If you’re in these fields, AI won’t necessarily take your job. But someone using AI might outperform you.

What to Do If Your Job Is on the AI-Hit List

  • Learn AI tools like Copilot, ChatGPT, Notion AI, etc.
  • Upskill into hybrid roles: combine tech + soft skills
  • Focus on creativity, judgment, and strategy
  • Adapt workflows to become an AI collaborator, not a competitor

Final Thoughts

This Microsoft study doesn’t predict mass unemployment. It highlights a new division in the workforce:

  • Jobs AI can assist or replace
  • Jobs AI can support but not perform

Knowledge work is shifting. Manual work is safer for now. But no job is truly future-proof. The key is to stay curious, keep learning, and work with AI, not against it.

Want to learn how autonomous AI is evolving beyond simple automation?

Read our deep-dive on Agentic AI and how it works to explore the next frontier in goal-driven artificial intelligence.

Source: Based on findings from a Microsoft study published on arXiv